What are the extreme effects of drug/alcohol abuse?

(D) There are several far-reaching and extreme implications of drug and alcohol abuse:
$1$. Financial and Social Impact: If a user is unable to obtain money to purchase drugs or alcohol,they may resort to stealing. The adverse effects extend beyond the individual; an addict often causes severe mental and financial distress to their entire family and friends.
$2$. Risk of Serious Infections: Individuals who take drugs intravenously (direct injection into the vein using a needle and syringe) are at a high risk of acquiring serious infections like $AIDS$ and Hepatitis $B$. These viruses are transmitted by sharing infected needles and syringes.
$3$. Chronic Health Consequences: Both $AIDS$ and Hepatitis $B$ are chronic,often fatal infections. Furthermore,chronic use of drugs and alcohol causes permanent damage to the nervous system and the liver,leading to conditions like cirrhosis.
$4$. Long-term and Developmental Effects: Alcohol use during adolescence can lead to heavy drinking patterns in adulthood. Additionally,the use of drugs and alcohol during pregnancy is known to adversely affect the development of the foetus.